期刊
ORGANIC LETTERS
卷 7, 期 18, 页码 3965-3968出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol0514754
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资金
- NIGMS NIH HHS [GM 58160] Funding Source: Medline
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM058160] Funding Source: NIH RePORTER
The Pd-catalyzed amination of a variety of heteroaryl halides has been accomplished by utilizing bulky electron-rich biaryl phosphine ligands. In particular, we report the first couplings of amines with chloro- and bromoindoles bearing a free NH, as well as the first Pd-catalyzed aminations of a 5-halopyrimidine.
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