期刊
CHEMICAL COMMUNICATIONS
卷 -, 期 2, 页码 265-267出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b412221f
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资金
- NATIONAL CANCER INSTITUTE [R37CA016954, R01CA016954] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM045026, R29GM045026] Funding Source: NIH RePORTER
- NCI NIH HHS [CA16954] Funding Source: Medline
- NIGMS NIH HHS [GM 45026] Funding Source: Medline
The experimental evidence presented in this manuscript suggest against the widely accepted single electron/proton transfer mechanism for P-450 catalyzed N-dealkylations and provides strong support for a hydrogen atom abstraction mechanism.
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