[5C+1N] Annulation: a novel synthetic strategy for functionalized 2,3-dihydro-4-pyridones

A novel and facile route to functionalized mono/bicyclic 2,3dihydro- 4-pyridones has been developed via formal [5C + 1N] annulation of readily available alpha-alkenoyl ketene-( S, S)-acetals with various aliphatic primary amines.