相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients
Srinivasa Rao Jada et al.
CANCER SCIENCE (2007)
Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer
Ji-Youn Han et al.
CANCER (2007)
Novel SLC22A16 polymorphisms and influence on doxorubicin pharmacokinetics in Asian breast cancer patients
Suman Lal et al.
PHARMACOGENOMICS (2007)
A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity
Vanessa Gonzalez-Covarrubias et al.
DRUG METABOLISM AND DISPOSITION (2007)
A silent polymorphism in the MDR1 gene changes substrate specificity
Chava Kimchi-Sarfaty et al.
SCIENCE (2007)
MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells
Noha N. Salama et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2006)
ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma
NY Frank et al.
CANCER RESEARCH (2005)
The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites
S Pratt et al.
MOLECULAR CANCER THERAPEUTICS (2005)
ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation
IA Hauser et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer
QY Zhou et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Clinical pharmacogenetics of immunosuppressive drugs in organ transplantation
T Szekerres et al.
PHARMACOGENOMICS (2005)
Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2
ER Lepper et al.
PHARMACOGENOMICS (2005)
Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3)
SS Lakhman et al.
DRUG METABOLISM AND DISPOSITION (2005)
Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta
D Kobayashi et al.
DRUG METABOLISM AND DISPOSITION (2005)
Hepatic technetium Tc 99m-labeled sestamibi elimination rate and ABCB1 (MDR1) genotype as indicators of ABCB1 (P-glycoprotein) activity in patients with cancer
M Wong et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)
CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation
D Anglicheau et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2004)
ABCG2 pharmacogenetics: Ethnic differences in allele frequency and assessment of influence on irinotecan disposition
FA de Jong et al.
CLINICAL CANCER RESEARCH (2004)
Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype
A Sparreboom et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2004)
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition
SY Yi et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2004)
Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1)
C Pauli-Magnus et al.
PHARMACEUTICAL RESEARCH (2004)
Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms
K Meissner et al.
PHARMACOGENETICS (2004)
Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene
DL Kroetz et al.
PHARMACOGENETICS (2003)
Pharmacogenetics of MDR1 and its impact on the pharmacokinetics of drugs and pharmacodynamics
T Sakaeda et al.
PHARMACOGENOMICS (2003)
MDR1 genotype-related duodenal absorption rate of digoxin in healthy Japanese subjects
Y Morita et al.
PHARMACEUTICAL RESEARCH (2003)
Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients
B Chowbay et al.
PHARMACOGENETICS (2003)
Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors
X Wang et al.
MOLECULAR PHARMACOLOGY (2003)
Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan
K Sai et al.
PHARMACOGENETICS (2003)
Determination of doxorubicin and its metabolites in rat serum and bile by LC: application to preclinical pharmacokinetic studies
QY Zhou et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2002)
Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene
A Johne et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2002)
Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein
Y Kurata et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2002)
MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine
S Drescher et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2002)
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
S Zhou et al.
NATURE MEDICINE (2001)
Identification of functionally variant MDR1 alleles among European Americans and African Americans
RB Kim et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2001)
Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines
DW Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells
S Kawabata et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin
S Awasthi et al.
BIOCHEMISTRY (2000)
Functional polymorphisms of the human multidrug-resistance gene:: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
S Hoffmeyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)