4.7 Article

Synthesis of urea oligomers and their antibacterial activity

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CHEMICAL COMMUNICATIONS
卷 -, 期 12, 页码 1537-1539

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ROYAL SOC CHEMISTRY
DOI: 10.1039/b413679a

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  1. NIGMS NIH HHS [R01-GM65803] Funding Source: Medline
  2. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM065803] Funding Source: NIH RePORTER

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Facially amphiphilic urea oligomers were successfully prepared in a one-pot reaction by carbonyl diimidazole (CDI) coupling and showed greater antibacterial activity against both Gram-negative Escherichia coli and Gram-positive Bacillus subtilis than MSI-78.

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