期刊
JOURNAL OF VIROLOGY
卷 79, 期 1, 页码 644-648出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.79.1.644-648.2005
关键词
-
类别
资金
- NIAID NIH HHS [R01 AI019244, AI19244] Funding Source: Medline
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI019244] Funding Source: NIH RePORTER
The ubiquitin-proteasome system is involved in cellular endocytosis and maturation of some viruses. In this study, we found that proteasome inhibitors blocked mouse hepatitis virus replication at an early step in the viral life cycle. In the presence of MG132, the entering viruses accumulated in both the endosome and denser lysosome, suggesting that the ubiquitin-proteasome system is involved in the release of virus from the endosome to the cytosol during the virus entry step.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据