期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 3, 期 16, 页码 2946-2952出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b503757c
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资金
- NIGMS NIH HHS [GM 069773] Funding Source: Medline
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM069773] Funding Source: NIH RePORTER
Synthesis and stability studies of exocyclic amino triazine nucleosides were performed. Stability of the nucleosides was found to be dependent on triazine ring electron density, solvent, and pH. The nucleosides were found to be more stable when the triazine ring was electron deficient, in high pH aqueous solutions and in aprotic solvents.
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