期刊
NANO LETTERS
卷 5, 期 1, 页码 113-117出版社
AMER CHEMICAL SOC
DOI: 10.1021/nl0482478
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- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [P41EB001976] Funding Source: NIH RePORTER
- NIBIB NIH HHS [9 P41 EB001976-16] Funding Source: Medline
A class of highly fluorescent and photostable core-shell nanoparticles from a modified Stober synthesis in the size range of 20-30 nm is described. These nanoparticles are monodisperse in solution, 20 times brighter, and more photostable than their constituent fluorophore, and are amenable to specific labeling of biological macromolecules for bioimaging experiments. The photophysical characteristics of the encapsulated fluorophores differ from their solution properties. This raises the possibility of tuning nanoparticle structure toward enhanced radiative properties, making them an attractive material platform for a diverse range of applications.
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