期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 139, 期 1, 页码 68-69出版社
SPRINGER
DOI: 10.1007/s10517-005-0214-5
关键词
Daphnia; embryotoxicity; selective acetylcholinesterase inhibitor; ammonium; uracyls
Chronic experiments on successive generations of laboratory Daphnia magna culture demonstrated higher (compared to proserin) embryotoxicity of a new selective acetylcholinesterase inhibitor 1,3-bis[5-(diethyl-o-nitrobenzilammonio)pentyl]-6-methyluracyl dibromide (compound No. 547). The concentrations of proserin (neostigmine) and compound No. 547 not exceeding 1/60 LC50 (0.39 mu mol/liter for compound No. 547 and 0.045 mu mol/liter for proserin) were absolutely safe for the reproductive function of daphnia.
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