4.7 Article

Flow-induced deformation of shallow microfluidic channels

期刊

LAB ON A CHIP
卷 6, 期 4, 页码 500-507

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/b513524a

关键词

-

资金

  1. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [P50GM068762] Funding Source: NIH RePORTER
  2. NIGMS NIH HHS [PSO-GM068762] Funding Source: Medline

向作者/读者索取更多资源

We study the elastic deformation of poly( dimethylsiloxane) (PDMS) microchannels under imposed flow rates and the effect of this deformation on the laminar flow profile and pressure distribution within the channels. Deformation is demonstrated to be an important consideration in low aspect ratio ( height to width) channels and the effect becomes increasingly pronounced for very shallow channels. Bulging channels are imaged under varying flow conditions by confocal microscopy. The deformation is related to the pressure and is thus non-uniform throughout the channel, with tapering occuring along the stream-wise axis. The measured pressure drop is monitored as a function of the imposed flow rate. For a given pressure drop, the corresponding flow rate in a deforming channel is found to be several times higher than expected in a non-deforming channel. The experimental results are supported by scaling analysis and computational fluid dynamics simulations coupled to materials deformation models.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据