期刊
DRYING TECHNOLOGY
卷 24, 期 7, 页码 849-861出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/07373930600734018
关键词
excipients; freeze-drying; freezing; optimal control; pressure rise method
Significance of pharmaceutical formulation (choosing of correct excipients in optimal quantities), effects of glass transition temperature, importance of theoretical modeling of the process, benefits of optimal control, and the advantages of remote monitoring of the process are presented. Experimental and theoretical research and development needs for the freeze-drying of pharmaceutical products are proposed and discussed.
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