期刊
JOURNAL OF PAEDIATRICS AND CHILD HEALTH
卷 42, 期 9, 页码 486-490出版社
BLACKWELL PUBLISHING
DOI: 10.1111/j.1440-1754.2006.00908.x
关键词
cancer risk; guideline; hepatoblastoma; overgrowth; Wilms tumour
类别
There is strong evidence for an association between overgrowth disorders such as Beckwith-Wiedemann syndrome and the development of neoplasia. An increased cancer risk has also been observed in individuals with isolated hemihyperplasia. We critically review the evidence for tumour surveillance in Beckwith-Wiedemann syndrome and isolated hemihyperplasia and suggest local practice guidelines.
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