期刊
DYES AND PIGMENTS
卷 70, 期 3, 页码 259-262出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.dyepig.2005.01.009
关键词
Metronidazole; Secnidazole; diazotization; beta-naphtol; spectrophotometry
A rapid and sensitive spectrophotometric method is proposed for determination of Metronidazole and Secnidazole. The method depends on the reduction of Metronidazole and Secnidazole molecule with zinc dust and hydrochloric acid flowed by diazotization and coupling with beta-naphtol to give red colored chromogens easily measured spectrophotometrically which has lambda(max) = 510 nm. The experimental conditions were optimized and Berr's law was obeyed over the applicable concentration ranges. Both techniques were applied successfully to a wide variety of pharmaceutical preparations. (c) 2005 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据