期刊
CURRENT OPINION IN STRUCTURAL BIOLOGY
卷 16, 期 3, 页码 288-298出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2006.05.011
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资金
- NCI NIH HHS [P30 CA008748] Funding Source: Medline
- NIGMS NIH HHS [R01 GM034504, GM034504] Funding Source: Medline
- NATIONAL CANCER INSTITUTE [P30CA008748] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM034504] Funding Source: NIH RePORTER
G-quadruplexes and Z-DNA are two important non-B forms of DNA architecture. Results on novel structural elements, folding and unfolding kinetics, and interactions with small molecules and proteins have been reported recently for these forms. These results will enhance our understanding of the biology of these structures and provide a platform for drug design.
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