Titanium dioxide-mediated Friedel-Crafts acylation of aromatic compounds in solvent-free condition under microwave irradiation

Friedel-Crafts acylation of different arenes was carried out in the presence of titanium dioxide under microwave irradiation in solvent-free condition. Activated substrates undergo acylation predominantly at the para -position. An efficient, simple, selective acylation reaction affords good yield of the products and the catalyst could be easily recovered and recycled.