期刊
ANNALS OF ONCOLOGY
卷 17, 期 -, 页码 VII46-VII48出版社
OXFORD UNIV PRESS
DOI: 10.1093/annonc/mdl949
关键词
ovarian cancer; molecular biology; technology; proteomics
类别
Ovarian cancer (OC) still represents the most lethal of gynecological malignancies with the chance for death in 5 years exceeding the chance for life. In recent years, the development of knowledge in molecular biology of OC coupled with the new technologies offers enormous opportunity to learn about aetiology of OC, and also give us a powerful tool for early diagnosis, prognosis and treatment of this disease. In particular, small cancer specimens from patients have become extremely informative thanks to techniques such as laser capture microdissection (LCM), tissue lysate arrays (TLAs), reverse trascriptase polymerase chain reaction (RT- PCR), and mass spectrometry. All of this coupled with advancements in bioinformatics have allowed the explosion of genomics, transcriptomics and proteomics. This paper focusses on the influence that advancement in the -omics'' bio-technology will reserve in OC diagnosis, prognostic characterization, and treatment.
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