期刊
FERTILITY AND STERILITY
卷 85, 期 1, 页码 121-127出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2005.07.1295
关键词
sperm; X-bearing spermatozoa; Y-bearing spermatozoa; dimensional attributes; haploid; dosomic
资金
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT [R01HD019505] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH [R01OH004061] Funding Source: NIH RePORTER
- NICHD NIH HHS [HD-19505] Funding Source: Medline
- NIOSH CDC HHS [OH-04061] Funding Source: Medline
Objective: To explore the dimensional attributes of haploid and disomic X-bearing and Y-bearing spermatozoa. Design: Morphometric evaluation of more than 2,000 X-bearing and Y-bearing spermatozoa after identification of the genotype with fluorescence in situ hybridization. Setting: Academic clinical and research andrology laboratory. Main Outcome Measure(s): Sperm head area, perimeter, long axis, short axis, shape factor, elliptical form factor (long axis/short axis), and tail length. Result(s): We found no differences in dimensions or dimensional distributions between X-bearing and Y-bearing spermatozoa, whether in the native or the decondensed state, or in oligozoospermic or normozoospermic men. There were inconsistent differences and a 70% overlap in the dimensions of haploid and disomic spermatozoa. The other 30% of sperm with disomic nuclei were either smaller or larger compared to haploid spermatozoa. Conclusion(s) There are no differences, or distinguishing characteristics, in dimensions or dimensional distributions between X-bearing and Y-bearing spermatozoa. Dimensional attributes do not discriminate between dysomic and haploid spermatozoa.
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