4.7 Article

Long-term survival of Parkinson's disease - A population-based study

期刊

JOURNAL OF NEUROLOGY
卷 253, 期 1, 页码 33-37

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SPRINGER HEIDELBERG
DOI: 10.1007/s00415-005-0916-7

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Parkinson's disease; mortality; prognosis; population-based study

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In a set of a population- based study, long-term survival of 59 prevalent PD patients was compared with that of individuals free of neurological diseases matched 1:2 by sex and age of enrolment. PD individuals, compared with reference subjects, showed a two-fold increased risk of death (OR 2.1; 95 % CI 1.4, 3.1). Among causes of death, pneumonia and cachexia were significantly more frequent among PD patients than among individuals free of neurological diseases. We confirmed in a long-term follow-up study an increased mortality among PD individuals compared with that of the general population.

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