期刊
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
卷 6, 期 9-10, 页码 2638-2650出版社
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2006.449
关键词
pluronic; block copolymer; nanostructures; hydrogel; drug delivery
The first part of this article reviewed the applications of nanostructures derived from Pluronic block copolymers that have potentials in the field of biomedical sciences. Pluronic block copolymers are used not only in drug delivery systems but also in gene and cancer therapies. In the second part, the chemical modifications of Pluronic copolymers and their applications in biomedical science were W reviewed. Chemical modifications of Pluronic copolymers not only improve the properties of the polymers but they also impart more attractive properties to the block copolymers. The common systems used to modify Pluronic copolymers are polyacrylic acids, polybases, and biodegradable polyesters. Pluronics were also modified at both ends with functional groups to improve the mechanical properties of hydrogels.
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