期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 4, 期 9, 页码 1641-1646出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b602696f
关键词
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Novel, economic and environmentally friendly one-pot three-component Knoevenagel/hydrogenation (K/H) and four-component Knoevenagel/hydrogenation/alkylation (K/H/A) reactions of ketones, CH-acids, dihydropyridines and alkyl halides using proline and proline/metal carbonate catalysis, respectively, have been developed. Many of the products of these K/H and K/H/A reactions have direct applications in pharmaceutical chemistry.
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