4.3 Article

Geniposide from Gardenia jasminoides attenuates neuronal cell death in oxygen and glucose deprivation-exposed rat hippocampal slice culture

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BIOLOGICAL & PHARMACEUTICAL BULLETIN
卷 29, 期 1, 页码 174-176

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PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/bpb.29.174

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geniposide; Gardenia jusminoides; OGD; hippocampal slice culture

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Geniposide from Gardenia jasminoides protected neuronal cells from damage in oxygen and glucose deprivation-exposed hippocampal slice culture. Geniposide showed a greater protective effect on the granule cell layer than on the pyramidal cell layer including CA 1 and CA 3. On the basis of the experimental results, geniposide may be a therapeutic agent for ischemia in patients.

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