Oxidative cyclization of aromatic aldehyde N-acylhydrazones by bis(trifluoroacetoxy)iodobenzene

Aromatic aldehyde N-acylhydrazones were oxidized into 2,5-disubstituted 1,3,4-oxadiazoles with bis(trifluoroacetoxy) iodobenzene in CHCl(3) or DMSO at room temperature in good to excellent yields.