期刊
JOURNAL OF BIOMECHANICS
卷 39, 期 12, 页码 2232-2240出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.jbiomech.2005.07.007
关键词
tissue engineering; yarn design; mechanical properties; textile; braid
资金
- NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES [R01AR046563] Funding Source: NIH RePORTER
- NIAMS NIH HHS [R01 AR46563-01] Funding Source: Medline
Tissue engineering requires the ability to design scaffolds with mechanical properties similar to those of the native tissue. Here, B. mori silk yarns are used as a model system to demonstrate the potential benefits and drawbacks of several textile methods used to fabricate tissue engineering scaffolds. Fibers are plied, twisted, cabled, braided, and/or textured to form several geometries with a wide range of mechanical outcomes. Predictable changes in ultimate tensile strength and stiffness are demonstrated following processing and as a function of test environment. The mechanical effects of increasing turns per inch and combining groups of fibers into higher-order yarn structures are demonstrated. Braids, one of the most commonly used textile structures, are shown to be limited by a change in stiffness following the locking-angle and therefore, potentially not the ideal structure for tissue engineering. Cabled yarns appear to allow the most flexibility in mechanical outcomes with a highly organized geometry. Twisted yarns, while more economical than cabled yarns, result in a higher stiffness and lower percent elongation at break than cabled yarns. (c) 2005 Elsevier Ltd. All rights reserved.
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