A new approach to the synthesis of fused pyrazoles: The synthesis of new pyrazolo [4,3-e][1,2,4]triazolo-[4,3-a]pyrimidine-4(5H)-imines

A new route for the synthesis of pyrazolo[4,3-e][1,2,4] triazolo[4,3-a] pyrimidine4(5H)-imines has been delineated through heterocyclization of suitably functionalized pyrazoles with phenylisothiocyanate followed by methylation, nucleophilic displacement with hydrazine, and finally cyclocondensation with orthoesters.