期刊
CYTOGENETIC AND GENOME RESEARCH
卷 116, 期 1-2, 页码 100-103出版社
KARGER
DOI: 10.1159/000097424
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资金
- NATIONAL INSTITUTE OF MENTAL HEALTH [R21MH069688] Funding Source: NIH RePORTER
- NIMH NIH HHS [MH069688] Funding Source: Medline
B chromosomes are often considered to be one of the most mysterious elements of karyotypes (Camacho, 2004). It is generally believed that mammalian B chromosomes do not contain any protein coding genes. The discovery of a conserved KIT gene in Canidae B chromosomes has changed this view. Here we performed analysis of sequences surrounding KIT in B chromosomes of the fox and raccoon dog. The presence of the RPL23A pseudogene was shown in canid B chromosomes. The 3' end fragment of the KDR gene was found in raccoon dog B chromosomes. The size of the B-specific fragment homologous to the autosome fragment was estimated to be a minimum of 480 kbp in both species. The origin and evolution of B chromosomes in Canidae are discussed. Copyright (c) 2007 S. Karger AG, Basel
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