期刊
VIRUS RESEARCH
卷 123, 期 1, 页码 19-29出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.virusres.2006.07.015
关键词
enterovirus 71; epidemiology; molecular typing
类别
资金
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI051292, R21AI055466] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [U01NS047537] Funding Source: NIH RePORTER
- NIAID NIH HHS [AI51292, AI55466] Funding Source: Medline
- NINDS NIH HHS [U01 NS047537] Funding Source: Medline
Widespread circulation of human enterovirus 71 was discovered in a prospective study of fecal samples obtained from healthy Norwegian children. Molecular characterization of the virus determined that it belonged to genotype Cl. Complete sequencing of this strain, HEV71 804/NO/03, revealed differences in the 5'UTR and polymerase with respect to more pathogenic genotypes that may explain its reduced neurovirulence. Published by Elsevier B.V.
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