Dendrimers as drug delivery vehicles: non-covalent interactions of bioactive compounds with dendrimers

This mini review highlights issues associated with the use of dendrimers as drug delivery vehicles. The review introduces dendrimers and summarizes findings on their use in vivo and in vitro. Specifically, this review is limited to examples wherein the drug is non-covalently associated with the dendrimer. Examples wherein the drug is covalently attached to the dendrimer are not discussed. (C) 2007 Society of Chemical Industry.