期刊
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
卷 18, 期 4, 页码 709-713出版社
SOC BRASILEIRA QUIMICA
DOI: 10.1590/S0103-50532007000400007
关键词
biocatalysis; (IS)-(-)-verbenone; oxidations; Nocardia corallina
The biotransformation of (S)-cis-verbenol with Nocardia corallina was investigated using two methods: Suspension of cells in a phosphate buffer (pH 7) with various substrate:cells ratios; and bioreactor of 3-L with cells in the culture media. Both gave (IS)-(-)-verbenone with excellent yields ranging from > 99 to 98%, at scale of 0.7 and 7 mmol respectively.
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