期刊
BIOCHIMIE
卷 89, 期 1, 页码 1-20出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biochi.2006.07.009
关键词
histone lysine methylation; demethylation; SET domain; JmjC domain; epigenetics
Histone lysine methylation plays a fundamental role in chromatin organization and function. This epigenetic mark is involved in many biological processes such as heterochromatin formation, chromosome X inactivation, genomic imprinting and transcriptional regulation. Here, we review recent advances in how histone lysine methylation participates in these biological events, and the enzymes that control histone lysine methylation and demethylation. (c) 2006 Elsevier Masson SAS. All rights reserved.
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