期刊
JOURNAL DE CHIRURGIE
卷 144, 期 2, 页码 97-104出版社
MASSON EDITEUR
DOI: 10.1016/S0021-7697(07)89480-4
关键词
colon; rectum; cancer; genetic; carcinogenesis
类别
Gene alterations which have been implicated in colorectal carcinogenesis are characterized by three major mechanisms: chromosomal instability, microsatellite instability, and epigenetic mechanisms (i.e., CpG island hypertnethylation). Progress in understanding of these genetic and epigenetic instabilities has led to advances in the individualization and characterization of more homogeneous sub-groups of colorectal tumors with regard to progression, prognosis and response to therapy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据