期刊
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
卷 11, 期 1, 页码 5-10出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ijid.2006.04.003
关键词
A(-)B(+) clostridium difficile; infectious diarrhea; bacterial genotyping
Clostridium difficile is a major cause of infectious diarrhea in hospitalized patients. Many pathogenic strains of Clostridium difficile produce two toxins TcdA and TcdB, both of which are pro-inflammatory and enterotoxic in human intestine. Clinically relevant toxin A-negative, toxin B-positive (A(-)B(+)) strains of Clostridium difficile that cause diarrhea and colitis in humans have been isolated with increasing frequency worldwide. This perspective describes these important toxin variant strains and highlights the need to use Clostridium difficile diagnostic methods that can detect both TcdA and TcdB. (c) 2006 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据