4.2 Article

L-proline as an efficient organo-catalyst for the synthesis of polyhydroquinoline via multicomponent Hantzsch reaction

期刊

LETTERS IN ORGANIC CHEMISTRY
卷 4, 期 1, 页码 16-19

出版社

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157017807780037405

关键词

Hantzsch reaction; multi-component reactions; L-proline; polyhydroquinoline; beta-dicarbonyl compound; aldehyde

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L-Proline has been found as an effective catalyst for the one pot synthesis of polyhydroquinoline derivatives via four component Hantzsch reaction. This method provides several advantages such as being environmentally benign, possessing high yields with increased variations of the substituents in the product and preparative simplicity.

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