期刊
CHEMICAL SOCIETY REVIEWS
卷 36, 期 8, 页码 1207-1226出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b611967k
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This tutorial review provides a historical sampling of synthetic efforts undertaken in our laboratory, which have led to the total syntheses of a range of small molecule natural products of potential interest in oncology. It has become evident that natural products, and structures clearly derivable from natural products, have a remarkable record in the treatment of cancer at the clinical level. It is likely that, with the growing power of chemical synthesis, small molecule natural products will play a continuing role in providing lead anticancer compounds.
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