4.5 Review

Artemisinin, promising lead natural product for various drug developments

期刊

MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 7, 期 4, 页码 411-422

出版社

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955707780363837

关键词

artemisinin; artemisinin derivatives; natural product; endoperoxide; lead compound; drug discovery

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Artemisinin and its synthetic derivatives are widely used for antimalarial agents in the world. Moreover, the), are discovered to additionally use as anticancer, antiangiogenesis, antiviral, immunosuppressive, and antifungal agents. Recent research results supported that it is a very promising field in drug discovery. In this review, it will discuss the structural and biological features of artemisinin and its derivatives that have published since 2003 except antimalarial, and show that they are useful lead compounds for novel drug discovery.

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