期刊
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
卷 11, 期 2, 页码 176-205出版社
WILEY
DOI: 10.1111/j.1582-4934.2007.00031.x
关键词
extracellular matrix; blood vessel formation; angiogenesis
资金
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL062289] Funding Source: NIH RePORTER
- NHLBI NIH HHS [R01 HL062289, HL 62289] Funding Source: Medline
The extracellular matrix plays a number of important roles, among them providing structural support and information to cellular structures such as blood vessels imbedded within it. As more complex organisms have evolved, the matrix ability to direct signalling towards the vasculature and remodel in response to signalling from the vasculature has assumed progressively greater importance. This review will focus on the molecules of the extracellular matrix, specifically relating to vessel formation and their ability to signal to the surrounding cells to initiate or terminate processes involved in blood vessel formation.
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