期刊
CANCER LETTERS
卷 275, 期 2, 页码 185-193出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.canlet.2008.10.015
关键词
Cancer stem cells; Tumour-initiating cells; Hepatocellular carcinoma; Colorectal carcinoma; Migration
类别
资金
- German Cancer AID (Deutsche Krebshilfe)
- German Federal Ministry of Education and Research (BMBF)
- Heidelberger Stiftung Chirurgie
Recent findings suggest that the presence of cancer stem cells could be linked with patients' survival. We profiled suggested cancer stem cell markers in tissue specimens of hepatocellular carcinoma and colorectal carcinoma liver metastases. About 1% of cells co-expressed cancer stem cell antigens, but there was no correlation between the amount of CD133(+), CD133(+)/CD44(+) or CD133(+)/CD24(-) cells and the patients' clinical-pathological status or with the cancer stem cell marker-positive cells localization. CD133(+) and CD133(-) fractions of Huh7 cells did not differ in migratory properties. Therefore, presence of markers alone should be taken with caution as single prognostic parameters. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据