4.2 Review

Genetically Engineered Mouse Models of Pancreatic Cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

Haoqiang Ying et al.

Article Developmental Biology

Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas

Daniel Kopinke et al.

DEVELOPMENTAL BIOLOGY (2012)

Review Gastroenterology & Hepatology

What We Have Learned About Pancreatic Cancer From Mouse Models

Pedro A. Perez-Mancera et al.

GASTROENTEROLOGY (2012)

Article Medicine, Research & Experimental

Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice

Meredith A. Collins et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Article Immunology

Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma

Natalie Cook et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2012)

Article Biochemistry & Molecular Biology

Changes in Connexin43 Expression and Localization During Pancreatic Cancer Progression

Joell L. Solan et al.

JOURNAL OF MEMBRANE BIOLOGY (2012)

Article Multidisciplinary Sciences

Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma

Karen M. Mann et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Anatomy & Morphology

Pancreas Organogenesis: From Bud to Plexus to Gland

Fong Cheng Pan et al.

DEVELOPMENTAL DYNAMICS (2011)

Review Chemistry, Medicinal

Inhibition of Ras for cancer treatment: the search continues

Antonio T. Baines et al.

FUTURE MEDICINAL CHEMISTRY (2011)

Article Medicine, General & Internal

Pancreatic cancer

Audrey Vincent et al.

LANCET (2011)

Article Biochemistry & Molecular Biology

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

Eric A. Collisson et al.

NATURE MEDICINE (2011)

Article Gastroenterology & Hepatology

OPINION From tissue turnover to the cell of origin for pancreatic cancer

Bo Kong et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2011)

Review Anatomy & Morphology

Animal transgenesis: an overview

Miguel A. Gama Sosa et al.

BRAIN STRUCTURE & FUNCTION (2010)

Article Oncology

PTEN Loss Accelerates KrasG12D-Induced Pancreatic Cancer Development

Reginald Hill et al.

CANCER RESEARCH (2010)

Article Medicine, Research & Experimental

β-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice

John P. Morris et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Biotechnology & Applied Microbiology

Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models

Mallika Singh et al.

NATURE BIOTECHNOLOGY (2010)

Review Medicine, General & Internal

Pancreatic Cancer

Manuel Hidalgo

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Multidisciplinary Sciences

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

Jennifer P. Morton et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma

Pawel K. Mazur et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Oncology

Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras

Sharon Y. Gidekel Friedlander et al.

CANCER CELL (2009)

Article Biochemistry & Molecular Biology

Mutant p53 Drives Invasion by Promoting Integrin Recycling

Patricia A. J. Muller et al.

Article Cell Biology

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E-coli, mammalian cells and mice

Konstantinos Anastassiadis et al.

DISEASE MODELS & MECHANISMS (2009)

Review Gastroenterology & Hepatology

Stem cells in gastroenterology and hepatology

Michael Quante et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2009)

Article Multidisciplinary Sciences

Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

Hua Tian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Oncology

Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer

Jennifer M. Bailey et al.

CLINICAL CANCER RESEARCH (2008)

Review Endocrinology & Metabolism

Minireview: Pancreatic progenitor cells - Recent studies

Hsun Teresa Ku

ENDOCRINOLOGY (2008)

Article Gastroenterology & Hepatology

Stabilization of β-catenin induces pancreas tumor formation

Patrick W. Heiser et al.

GASTROENTEROLOGY (2008)

Article Biochemistry & Molecular Biology

Pancreatic Lkb1 deletion leads to acinar polarity defects and cystic neoplasms

Aram F. Hezel et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Article Multidisciplinary Sciences

A Cre-IoXP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors

Barbara Seidler et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

De La O. Jean-Paul et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia

Catherine Carriere et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse

N Bardeesy et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Cell Biology

Dissecting the cellular origins of pancreatic cancer

BZ Stanger et al.

CELL CYCLE (2006)

Article Multidisciplinary Sciences

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

SP Thayer et al.

NATURE (2003)

Article Multidisciplinary Sciences

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

L Johnson et al.

NATURE (2001)