期刊
DEPRESSION AND ANXIETY
卷 24, 期 7, 页码 495-517出版社
WILEY
DOI: 10.1002/da.20262
关键词
GABA; anxiety; depression; benzodiazepine receptors; common pathogenesis
资金
- Intramural NIH HHS Funding Source: Medline
This review assesses the parallel data on the role of gamma-aminobutyric acid (GABA) in depression and anxiety. We review historical and new data from both animal and human experimentation which have helped define the key role for this transmitter in both these mental pathologies. By exploring the overlap in these conditions in terms of GABAergic neurochemistry, neurogenetics, brain circuitry, and pharmacology, we develop a theory that the two conditions are intrinsically interrelated. The role of GABAergic agents in demonstrating this interrelationship and in pointing the way to future research is discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据