期刊
CURRENT OPINION IN PSYCHIATRY
卷 20, 期 1, 页码 17-22出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/YCO.0b013e3280106868
关键词
attempted suicide; committed sucide; mood disorders; suicidal ideation; suicide risk factors
类别
Purpose of review The aim of this review is to highlight the traditional and newly recognized suicide risk factors in patients with mood disorders. Recent findings Current research findings clearly suggest that suicidal behaviour in patients with mood disorder is a 'state-dependent' phenomenon. Recently, there is, however, a growing body of evidence that besides the well accepted clinically explorable suicide risk factors in mood disorders (e.g., severe depression, prior suicide attempt, comorbid anxiety, substance use, personality disorders and so on), mixed state of depression could also be an important precursor of suicidal behaviour. This might be particularly true in unrecognized cases of bipolar depressives, when antidepressant monotherapy (unprotected by mood stabilizers or atypical antipsychotics) can worsen the clinical picture and rarely induce an aggressive or self-destructive behaviour. Summary In the majority of patients with mood disorders, suicidal behaviour is predictable and preventable, with a good chance. A careful and systematic exploration of suicide risk factors in patients with mood disorder helps clinicians to identify patients at high suicide risk. A successful, acute and long-term treatment of these patients substantially reduces the suicidal behaviour even in this high-risk population.
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