期刊
CANCER GENETICS AND CYTOGENETICS
卷 203, 期 2, 页码 328-332出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cancergencyto.2010.08.018
关键词
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Unclassifiable lymphoma with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma is a new category of B-cell lymphoma appearing in the new World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues. This lymphoma usually shows MYC rearrangements with non-IGH genes in the setting of a complex karyotype possibly involving BCL2 and, less frequently, BCL6 rearrangements. According to the presence of two or three rearrangements, these lymphomas are called double-hit lymphomas or triple-hit lymphomas (THL), respectively. Here we report two cases of THL with MYC. BCL2, and BCL6 rearrangements and t(3;8)(q27;q24) diagnosed in one center in the last two years. (C) 2010 Elsevier Inc. All rights reserved.
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