4.6 Review

Recent advances in p53 research: an interdisciplinary perspective

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Article Biochemistry & Molecular Biology

PML enhances the regulation of p53 by CK1 in response to DNA damage

O. Alsheich-Bartok et al.

ONCOGENE (2008)

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Functional evolution of the p53 regulatory network through its target response elements

Anil G. Jegga et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

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Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72

M. Reinbold et al.

ONCOGENE (2008)

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Mutant p53 R270H gain of function phenotype in a mouse model for oncogene-induced mammary carcinogenesis

Christina Heinlein et al.

INTERNATIONAL JOURNAL OF CANCER (2008)

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Contribution of membrane localization to the apoptotic activity of PUMA

Karen S. Yee et al.

APOPTOSIS (2008)

Review Biochemistry & Molecular Biology

DNA damage signalling guards against activated oncogenes and tumour progression

J. Bartek et al.

ONCOGENE (2007)

Review Oncology

Inflammation and cancer: An ancient link with novel potentials

S. Perwez Hussain et al.

INTERNATIONAL JOURNAL OF CANCER (2007)

Article Biochemistry & Molecular Biology

The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP

Fiamma Mantovani et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)

Article Multidisciplinary Sciences

Quantitative analyses reveal the importance of regulated Hdmx degradation for P53 activation

Yunyuan V. Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Cell Biology

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices

Gilles Gadea et al.

JOURNAL OF CELL BIOLOGY (2007)

Article Gastroenterology & Hepatology

Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture

Sabine Roman et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)

Review Cell Biology

p53: new roles in metabolism

Karim Bensaad et al.

TRENDS IN CELL BIOLOGY (2007)

Article Oncology

p53 therapy in a patient with Li-Fraumeni syndrome

Neil Senzer et al.

MOLECULAR CANCER THERAPEUTICS (2007)

Article Multidisciplinary Sciences

Inactivation of the p53 pathway in retinoblastoma

Nikia A. Laurie et al.

NATURE (2006)

Article Multidisciplinary Sciences

Structural basis for understanding oncogenic p53 mutations and designing rescue drugs

Andreas C. Joerger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Genetics & Heredity

Impact of the MDM2 SNP309 and p53 Arg72Pro polymorphism on age of tumour onset in Li-Fraumeni syndrome

G. Bougeard et al.

JOURNAL OF MEDICAL GENETICS (2006)

Article Multidisciplinary Sciences

Core domain interactions in full-length p53 in solution

DB Veprintsev et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Oncology

A twist for survival and cancer progression

A Puisieux et al.

BRITISH JOURNAL OF CANCER (2006)

Article Gastroenterology & Hepatology

Prevalence of early onset colorectal cancer in 397 patients with classic Li-Fraumeni syndrome

P Wong et al.

GASTROENTEROLOGY (2006)

Article Biochemistry & Molecular Biology

Tumor-derived p53 mutants induce NF-κB2 gene expression

MJ Scian et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Cell Biology

p53 isoforms can regulate p53 transcriptional activity

JC Bourdon et al.

GENES & DEVELOPMENT (2005)

Article Biochemistry & Molecular Biology

Epigenetic mechanisms affect mutant p53 transgene expression in WAP-mutp53 transgenic mice

F Krepulat et al.

ONCOGENE (2005)

Article Biochemistry & Molecular Biology

Crystal structure of a superstable mutant of human p53 core domain - Insights into the mechanism of rescuing oncogenic mutations

AC Joerger et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors

N Issaeva et al.

NATURE MEDICINE (2004)

Article Multidisciplinary Sciences

Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

S Kato et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Repeated observation of breast tumor subtypes in independent gene expression data sets

T Sorlie et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Regulation of Cdc42-mediated morpholigical effects:: a novel function for p53

G Gadéa et al.

EMBO JOURNAL (2002)

Article Biochemistry & Molecular Biology

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound

VJN Bykov et al.

NATURE MEDICINE (2002)

Article Multidisciplinary Sciences

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

T Sorlie et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Multidisciplinary Sciences

A inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

RC Ribeiro et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)