期刊
CHEMOTHERAPY
卷 53, 期 1, 页码 21-25出版社
KARGER
DOI: 10.1159/000098246
关键词
nitrofurantoin; enterobacteria; monoterpenes; carvone; piperitone; essential oils
Background: Piperitone from plant essential oils enhances bactericidal activities of nitrofurantoin and furazolidone against bacteria from the family Enterobacteriaceae. In this study, the essential oils of spearmint ( Mentha spicata L.), dill ( Anethum graveolens L.) and peppermint ( Mentha piperita L.) were screened for augmentation of nitrofurantoin activity and the most active components were determined. Method: The effects of essential oils and their components on the bactericidal activity of nitrofurantoin against Enterobacter cloacae were studied using disk-diffusion and agar-dilution methods. The composition of essential oils was studied using gas chromatography-mass spectrometry. Results: M. spicata and A. graveolens oils exhibited the highest effects. Gas chromatography-mass spectrometry analysis showed that the oils of these two plants contained 40.12 and 20.32% carvone, respectively. Pure carvone and piperitone equally increased the bactericidal activity of nitrofurantoin. Other ingredients of essential oils, including camphor, limonene and menthone, were less effective. Copyright (c) 2007 S. Karger AG, Basel
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据