期刊
ANNALS OF NONINVASIVE ELECTROCARDIOLOGY
卷 12, 期 1, 页码 64-78出版社
BLACKWELL PUBLISHING
DOI: 10.1111/j.1542-474X.2007.00140.x
关键词
K+ current; I-Ks; cardiac action potential; repolarization reserve; arrhythmias; long-QT syndrome
The aim of this review is to present the properties of the slow component of the delayed rectifier potassium current (I-Ks) in the human ventricle. The review gives a detailed description of the physiology, molecular biology and pharmacology of the I-Ks current, including kinetic properties, genetic structures, agonists and antagonists. The authors also present the role of the I-Ks current in the human cardiac repolarization focusing on several pathophysiological situations, such as the LQT syndrome and the Torsade de Pointes arrhythmia.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据