期刊
ANALYTICAL METHODS
卷 7, 期 5, 页码 1971-1976出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ay02843k
关键词
-
资金
- National Natural Science Foundation of China [91232703, 21127008, 21105133]
- Major National Scientific Instrument and Equipment Development Project [2011YQ03012409]
In this paper, a novel electrochemical method is proposed for the determination of 5-hydroxytryptophan (5-HTP) based on a carbon nanosheets (CNSs)-modified electrode. The CNSs were prepared by a one-step flowing electrolysis using a home-made device. The surface morphology and composition of the CNSs were characterized by scanning electron microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy. The cyclic voltammetry method was used to study the electrochemical behavior of 5-HTP on the CNSs-modified electrode. The results suggested that the modified electrode exhibited high electrocatalytic activity, and that the anodic peak current of 5-HTP was significantly enhanced on the modified electrode. A differential pulse voltammetry method was developed for the determination 5-HTP at the modified electrode. In the optimum experimental conditions, the linear calibration range varied from 5 x 10(-8) mol L-1 to 1 x 10(-6) mol L-1, with a detection limit of 3 x 10(-8) mol L-1. The proposed method was further successfully applied for the determination of 5-HTP in rats' brain tissue samples, with the recovery ranging from 90.3% to 98.0%.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据