期刊
CANCER CELL
卷 22, 期 5, 页码 567-568出版社
CELL PRESS
DOI: 10.1016/j.ccr.2012.10.008
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资金
- NCI NIH HHS [R01 CA101774] Funding Source: Medline
In this issue of Cancer Cell, Gruber et al. report that a significant proportion of children with acute megakaryoblastic leukemia acquire a translocation that confers enhanced BMP signaling and promotes self-renewal of hematopoietic progenitors. This study presents novel therapeutic targets that may lead to improved therapies for this aggressive leukemia.
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