期刊
CANCER CELL
卷 20, 期 4, 页码 420-423出版社
CELL PRESS
DOI: 10.1016/j.ccr.2011.10.004
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资金
- NCI NIH HHS [R01 CA151949, P30 CA008748, R01 CA151949-01] Funding Source: Medline
Reports of whole-exome sequencing in myelodysplastic syndrome (MDS) patients by Yoshida et al. and Papaemmanuil et al. suggest spliceosome mutations have clinical relevance. Identifying the impact of these mutations on MDS pathogenesis holds promise for therapeutic modulation of mRNA splicing.
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