期刊
CANCER CAUSES & CONTROL
卷 23, 期 2, 页码 281-288出版社
SPRINGER
DOI: 10.1007/s10552-011-9877-6
关键词
Human Papillomavirus (HPV); Cervical intraepithelial neoplasia (CIN); Cervical adenocarcinoma in situ (AIS); Post-licensure vaccine effectiveness; Vaccine impact; Surveillance
The following paper describes a collaboration between the Centers for Disease Control and Prevention and five Emerging Infections Program sites to develop a comprehensive population-based approach to monitoring human papillomavirus (HPV) vaccine impact on cervical cancer precursors and associated HPV genotypes. The process of establishing this novel monitoring system is described, and development details such as enumeration of sources for reporting cervical intraepithelial neoplasia 2/3 and adenocarcinoma in situ, approaches to case ascertainment, electronic reporting, and HPV typing are outlined. Implementation of a feasible and sustainable surveillance system for HPV-associated cervical precancers will enable evaluation of the direct impact of HPV vaccination.
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