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Ahmedin Jemal et al.
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Qi-Wen Fan et al.
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Saskia M. Brachmann et al.
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Anthony C. Faber et al.
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L. Makowski et al.
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Xuerong Wang et al.
CANCER BIOLOGY & THERAPY (2008)
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Violeta Serra et al.
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Beth Levine et al.
CELL (2008)
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Jaclyn LoPiccolo et al.
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Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
Sauveur-Michel Maira et al.
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Somatic mutations affect key pathways in lung adenocarcinoma
Li Ding et al.
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Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
Jeffrey A. Engelman et al.
NATURE MEDICINE (2008)
Potential therapeutic applications of autophagy
David C. Rubinsztein et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Ras, PI(3)K and mTOR signalling controls tumour cell growth
Reuben J. Shaw et al.
NATURE (2006)
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BT Hennessy et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Autophagy in cell death: an innocent convict?
B Levine et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
The LKB1 tumor suppressor negatively regulates mTOR signaling
RJ Shaw et al.
CANCER CELL (2004)
Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells
XG Liu et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2004)
Activation of the PI3K/Akt pathway and chemotherapeutic resistance
KA West et al.
DRUG RESISTANCE UPDATES (2002)
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
C Lois et al.
SCIENCE (2002)
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