期刊
JOURNAL OF BONE AND MINERAL RESEARCH
卷 22, 期 1, 页码 149-157出版社
WILEY
DOI: 10.1359/JBMR.061011
关键词
finite element analysis; teriparatide; PTH(1-34); alendronate; bone strength; bone quality
FE modeling was used to estimate the biomechanical effects of teriparatide and alendronate on lumbar vertebrae. Both treatments enhanced predicted vertebral strength by increasing average density. This effect was more pronounced for teriparatide, which further increased predicted vertebral strength by altering the distribution of density within the vertebra, preferentially increasing the strength of the trabecular compartment.
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