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Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo
Guangyu Gu et al.
CANCER RESEARCH (2007)
Cancer stem-like cells in human prostate carcinoma cells DU145 - The seeds of the cell line?
Chen Wei et al.
CANCER BIOLOGY & THERAPY (2007)
CD133+ and CD133- glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles
Dagmar Beier et al.
CANCER RESEARCH (2007)
Ionising radiation induces changes associated with epithelial-mesenchymal transdifferentiation and increased cell motility of A549 lung epithelial cells
Jae-Won Jung et al.
EUROPEAN JOURNAL OF CANCER (2007)
Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells
A. Iwamaru et al.
ONCOGENE (2007)
Crosstalk between Bak/Bax and mTOR signaling regulates radiation-induced autophagy
Luigi Moretti et al.
AUTOPHAGY (2007)
被撤回的出版物: Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo (Retracted article. See vol. 78, pg. 6028, 2018)
Julian J. Raffoul et al.
CANCER RESEARCH (2007)
Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor
J. An et al.
ONCOGENE (2007)
WNT/β-catenin mediates radiation resistance of mouse mammary progenitor cells
Wendy A. Woodward et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Knock-down of Bcl-2 by antisense oligodeoxynucleotides induces radiosensitization and inhibition of angiogenesis in human PC-3 prostate tumor xenografts
Satoshi Anai et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Prostate cancer stem/progenitor cells: Identification, characterization, and implications
Dean G. Tang et al.
MOLECULAR CARCINOGENESIS (2007)
Role of autophagy in cancer - Management of metabolic stress
Shengkan Jin et al.
AUTOPHAGY (2007)
The response of CD24-/low/CD44+ breast cancer-initiating cells to radiation
Tiffany M. Phillips et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao et al.
NATURE (2006)
Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-κB signal transduction pathway
J. C-H Cheng et al.
ONCOGENE (2006)
Prostate cancer metastasis: Role of the host microenvironment in promoting epithelial to mesenchymal transition and increased bone and adrenal gland metastasis
Jianchun Xu et al.
PROSTATE (2006)
Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells
Carolyn Cao et al.
CANCER RESEARCH (2006)
External-beam radiotherapy for localized prostate cancer
Thomas M. Pisansky
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Combination of PTEN gene therapy and radiation inhibits the growth of human prostate cancer Xenografts
Satoshi Anai et al.
HUMAN GENE THERAPY (2006)
Down-regulation of Hsp27 radiosensitizes human prostate cancer cells
Shahram Teimourian et al.
INTERNATIONAL JOURNAL OF UROLOGY (2006)
Expression of mTOR signaling pathway markers in prostate cancer progression
Celeste L. Kremer et al.
PROSTATE (2006)
Prostate cancer treatment is enhanced by genistein in vitro and in vivo in a syngeneic orthotopic tumor model
Yu Wang et al.
RADIATION RESEARCH (2006)
Prostate cancer stem cells
Anne T. Collins et al.
EUROPEAN JOURNAL OF CANCER (2006)
Synergistic effects of radiation and β-lapachone in DU-145 human prostate cancer cells in vitro
M Suzuki et al.
RADIATION RESEARCH (2006)
Sunitinib malate for the treatment of solid tumours: a review of current clinical data
Robert J. Motzer et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2006)
Genistein inhibits radiation-induced activation of NF-κB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest
Julian J. Raffoul et al.
BMC CANCER (2006)
A matter of life or death (or both): Understanding autophagy in cancer
WN Hait et al.
CLINICAL CANCER RESEARCH (2006)
N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1
NR Alexander et al.
CANCER RESEARCH (2006)
Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
L Patrawala et al.
ONCOGENE (2006)
Combination of celecoxib with percutaneous radiotherapy in patients with localised prostate cancer - a phase I study
U. Ganswindt et al.
RADIATION ONCOLOGY (2006)
Involvement of PI3K/Akt pathway in prostate cancer -: Potential strategies for developing targeted therapies
N Pommery et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2005)
Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells
S Paglin et al.
CANCER RESEARCH (2005)
Prospective identification of tumorigenic prostate cancer stem cells
AT Collins et al.
CANCER RESEARCH (2005)
Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism
AR Gottschalk et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
Radiation and the microenvironment - Tumorigenesis and therapy
MH Barcellos-Hoff et al.
NATURE REVIEWS CANCER (2005)
Comparison of conventional-dose vs high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate - A randomized controlled trial
AL Zietman et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)
Opinion - Migrating cancer stem cells - an integrated concept of malignant tumour progression
T Brabletz et al.
NATURE REVIEWS CANCER (2005)
Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis
JH Kim et al.
CANCER RESEARCH (2005)
The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism
F Pajonk et al.
BMC CANCER (2005)
Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis
JP Truman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target
WK Kwok et al.
CANCER RESEARCH (2005)
Modulation of radiation response by histone deacetylase inhibition
P Chinnaiyan et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
Frequent genetic and biochemical alterations of the PI3-K/AKT/PTEN pathway in head and neck squamous cell carcinoma
JMG Pedrero et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Combined ionizing radiation and sKDR gene delivery for treatment of prostate carcinomas
SA Kaliberov et al.
GENE THERAPY (2005)
Synergistic cytotoxic effects of zoledronic acid and radiation in human prostate cancer and myeloma cell lines
E Algur et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
Silencing of the IGF1R gene enhances sensitivity to DNA-damaging agents in both PTEN wild-type and mutant human prostate cancer
MA Rochester et al.
CANCER GENE THERAPY (2005)
The role of autophagy in cancer development and response to therapy
Y Kondo et al.
NATURE REVIEWS CANCER (2005)
Redox modulation of human prostate carcinoma cells by selenite increases radiation-induced cell killing
B Husbeck et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Autophagy as a cell death and tumor suppressor mechanism
D Gozuacik et al.
ONCOGENE (2004)
Adenoviral-mediated PTEN transgene expression sensitizes Bcl-2-expressing prostate cancer cells to radiation
CJ Rosser et al.
CANCER GENE THERAPY (2004)
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
LT Vassilev et al.
SCIENCE (2004)
Antisense MDM2 sensitizes prostate cancer cells to androgen deprivation, radiation, and the combination
ZM Mu et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2004)
AEE788: A dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity
P Traxler et al.
CANCER RESEARCH (2004)
CD133, a novel marker for human prostatic epithelial stem cells
GD Richardson et al.
JOURNAL OF CELL SCIENCE (2004)
The biology and clinical relevance of the PTEN tumor suppressor pathway
I Sansal et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
A specific antagonist of the p110δ catalytic component of phosphatidylinositol 3′-kinase, IC486068, enhances radiation-induced tumor vascular destruction
L Geng et al.
CANCER RESEARCH (2004)
The complexity of PTEN: mutation, marker and potential target for therapeutic intervention
LS Steelman et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2004)
Phosphatidylinositol 3′-kinase activation leads to multidrug resistance protein-1 expression and subsequent chemoresistance in advanced prostate cancer cells
JT Lee et al.
CANCER RESEARCH (2004)
Radical prostatectomy, external beam radiotherapy > 72 Gy, external beam radiotherapy <= 72 Gy, permanent seed implantation, or combined seeds/external beam radiotherapy for stage T1-T2 prostate cancer
PA Kupelian et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2004)
Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells
S Zhang et al.
CANCER LETTERS (2004)
Serine/threonine kinase AKT is frequently activated in human bile duct cancer and is associated with increased radioresistance
S Tanno et al.
CANCER RESEARCH (2004)
The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas
A Chakravarti et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
The TOR pathway: A target for cancer therapy
MA Bjornsti et al.
NATURE REVIEWS CANCER (2004)
Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers
HK Lin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Recurrent prostate cancer following external beam radiotherapy: Follow-up strategies and management
C Catton et al.
UROLOGIC CLINICS OF NORTH AMERICA (2003)
Discovery, characterization, and structure - Activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins
S Kitada et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
SY Wang et al.
CANCER CELL (2003)
The RAS signal transduction pathway and its role in radiation sensitivity
WG McKenna et al.
ONCOGENE (2003)
Unravelling the activation mechanisms of protein kinase B/Akt
MP Scheid et al.
FEBS LETTERS (2003)
Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells
MC Zhang et al.
BIOCHEMICAL PHARMACOLOGY (2003)
Long-term cancer control of radical prostatectomy in men younger than 50 years of age: Update 2003
MA Khan et al.
UROLOGY (2003)
Role of radiation therapy and radiosurgery in glioblastoma multiforme
JB Fiveash et al.
CANCER JOURNAL (2003)
Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIk3CA amplification in gastric carcinoma
DS Byun et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
Didox (A novel ribonucleotide reductase inhibitor) overcomes bcl-2 mediated radiation resistance in prostate cancer cell line PC-3
MS Inayat et al.
CANCER BIOLOGY & THERAPY (2002)
Prostate cancer radiation dose response: Results of the M. D. Anderson phase III randomized trial
A Pollack et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2002)
The phosphatidylinositol 3-kinase-AKT pathway in human cancer
I Vivanco et al.
NATURE REVIEWS CANCER (2002)
The protein kinase B/Akt signalling pathway in human malignancy
KM Nicholson et al.
CELLULAR SIGNALLING (2002)
Additional gene therapy with Ad5CMV-p53 enhanced the efficacy of radiotherapy in human prostate cancer cells
R Sasaki et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2001)
The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
S Arico et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Adenoviral-mediated p53 transgene expression sensitizes both wild-type and null p53 prostate cancer cells in vitro to radiation
PJ Colletier et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2000)
Synthesis of NF-κB activation inhibitors derived from epoxyquinomicin C
N Matsumoto et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2000)
Mutation and allelic loss of the PTEN/MMAC1 gene in primary and metastatic melanoma biopsies
A Birck et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2000)
Radiation induces upregulation of cyclooxygenase-2 (COX-2) protein in PC-3 cells
KK Steinauer et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2000)
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